Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change (NCT03191149)
Phase II Study of Osimertinib (AZD9291) in Advanced NSCLC Patients With Exon 20 Insertion Mutations in EGFR
๐ฉบ Plain-English Summary (8th-Grade Level)
This phase II trial studies how well osimertinib works in treating patients with non-small cell lung cancer with EGFR exon 20 insertion mutation that is stage IIIB-IV or has come back after a period of improvement (recurrent). Osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Who can join: Review the eligibility criteria below.
Location: Anchorage Associates in Radiation Medicine โ Anchorage, Alaska
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (344 Sites)
Showing the first 25 of 344 sites.
- Anchorage Associates in Radiation Medicine โ Anchorage, Alaska
- Anchorage Radiation Therapy Center โ Anchorage, Alaska
- Alaska Breast Care and Surgery LLC โ Anchorage, Alaska
- Alaska Oncology and Hematology LLC โ Anchorage, Alaska
- Alaska Women's Cancer Care โ Anchorage, Alaska
- Anchorage Oncology Centre โ Anchorage, Alaska
- Katmai Oncology Group โ Anchorage, Alaska
- Providence Alaska Medical Center โ Anchorage, Alaska
- Fairbanks Memorial Hospital โ Fairbanks, Alaska
- Mercy Hospital Fort Smith โ Fort Smith, Arkansas
- CARTI Cancer Center โ Little Rock, Arkansas
- Providence Saint Joseph Medical Center/Disney Family Cancer Center โ Burbank, California
- MedStar Georgetown University Hospital โ Washington D.C., District of Columbia
- Holy Cross Hospital โ Fort Lauderdale, Florida
- Emory University Hospital Midtown โ Atlanta, Georgia
- Emory University Hospital/Winship Cancer Institute โ Atlanta, Georgia
- Emory Saint Joseph's Hospital โ Atlanta, Georgia
- Saint Alphonsus Cancer Care Center-Boise โ Boise, Idaho
- Saint Luke's Cancer Institute - Boise โ Boise, Idaho
- Saint Alphonsus Cancer Care Center-Caldwell โ Caldwell, Idaho
- Kootenai Health - Coeur d'Alene โ Coeur d'Alene, Idaho
- Walter Knox Memorial Hospital โ Emmett, Idaho
- Saint Luke's Cancer Institute - Fruitland โ Fruitland, Idaho
- Idaho Urologic Institute-Meridian โ Meridian, Idaho
- Saint Luke's Cancer Institute - Meridian โ Meridian, Idaho
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Lung Non-Small Cell Carcinoma
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- Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors โ Orange, California
- Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) โ Birmingham, Alabama
- Minnelide and Osimertinib for the Treatment of Advanced EGFR Mutated Non-Small Cell Lung Cancer โ Duarte, California
- CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer โ Buffalo, New York
- Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer โ Duarte, California
Explore by condition: All Advanced Lung Non-Small Cell Carcinoma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.