πŸ›οΈ Verified NIH Record β€’ Updated 2026-03-09

AMPLATZER PFO Occluder Post Approval Study (NCT03309332)

OSB Lead-AMPLATZER PFO Occluder New Enrollment PAS

πŸ”΅ Active, Not Recruiting Observational / Diagnostic βš™οΈ Medical Device Protocol Sponsor: Abbott Medical Devices

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this single arm, multi-center study is to confirm the safety and effectiveness of the AMPLATZERβ„’ PFO Occluder in the post Approval Setting.

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham β€” Birmingham, Alabama

Age range: 18 Years to 60 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (88 Sites)

Showing the first 25 of 88 sites.

  • University of Alabama at Birmingham β€” Birmingham, Alabama
  • Heart Center Research, LLC β€” Huntsville, Alabama
  • Chandler Regional Medical Center β€” Chandler, Arizona
  • St. Joseph's Hospital and Medical Center β€” Phoenix, Arizona
  • Scottsdale Healthcare Shea β€” Scottsdale, Arizona
  • Pima Heart Physicians, PC β€” Tucson, Arizona
  • UAMS Medical Center β€” Little Rock, Arkansas
  • Kaiser Permanente Los Angeles Medical Center β€” Los Angeles, California
  • USC University Hospital β€” Los Angeles, California
  • Ronald Reagan UCLA Medical Center β€” Los Angeles, California
  • Sutter Medical Center β€” Sacramento, California
  • San Diego Cardiac Center β€” San Diego, California
  • University of California at San Francisco β€” San Francisco, California
  • Stanford University Medical Center β€” Stanford, California
  • Los Robles Hospital and Medical Center β€” Thousand Oaks, California
  • University of Colorado Hospital β€” Aurora, Colorado
  • Memorial Hospital of Colorado Springs β€” Colorado Springs, Colorado
  • Denver Heart β€” Denver, Colorado
  • South Denver Cardiology Associates PC β€” Littleton, Colorado
  • MedStar Washington Hospital Center β€” Washington D.C., District of Columbia
  • St. Vincent's Medical Center β€” Jacksonville, Florida
  • Baptist Medical Center β€” Jacksonville, Florida
  • First Coast Cardiovascular Institute β€” Jacksonville, Florida
  • Orlando Health β€” Orlando, Florida
  • Cleveland Clinic Florida β€” Weston, Florida

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Stroke clinical trials

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—