๐๏ธ Verified NIH Record โข Updated 2026-02-26
Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity (NCT03318094)
Vanderbilt University Medical Center
๐ต Active, Not Recruiting Phase1 ๐ Investigational Drug / Biologic Sponsor: Vanderbilt University Medical Center
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to better understand the contribution of sympathetic vasoconstriction to impaired insulin-mediated vasodilation and subsequently insulin-mediated glucose uptake. The investigators will test the hypothesis that removal of sympathetic vasoconstriction can result in improvement in insulin-mediated vasodilation and subsequently sensitivity to insulin-mediated glucose uptake.
Who can join: Review the eligibility criteria below.
Location: Autonomic Dysfunction Center โ Nashville, Tennessee
Age range: 18 Years to 60 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- Autonomic Dysfunction Center โ Nashville, Tennessee
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Insulin Resistance
- Muscle Insulin Resistance in Aging (Mirage) โ Orlando, Florida
- Fructose: Substrate, Stimulus, or Both? โ Vallejo, California
- Insulin Resistance in HCV Infection โ San Francisco, California
- Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity โ Bethesda, Maryland
- Alpelisib Challenge Test (ACT) โ New York, New York
Explore by condition: All Insulin Resistance clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.