๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-12

Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer (NCT03348631)

A Phase II Study of Tazemetostat (EPZ-6438) in Recurrent or Persistent Endometrioid or Clear Cell Carcinoma of the Ovary, and Recurrent or Persistent Endometrioid Endometrial Adenocarcinoma

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase II trial studies how well tazemetostat works in treating patients with ovarian or endometrial cancer that has come back (recurrent). Chemotherapy drugs, such as tazemetostat, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Who can join: Review the eligibility criteria below.

Location: Anchorage Associates in Radiation Medicine โ€” Anchorage, Alaska

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (582 Sites)

Showing the first 25 of 582 sites.

  • Anchorage Associates in Radiation Medicine โ€” Anchorage, Alaska
  • Anchorage Radiation Therapy Center โ€” Anchorage, Alaska
  • Alaska Breast Care and Surgery LLC โ€” Anchorage, Alaska
  • Alaska Oncology and Hematology LLC โ€” Anchorage, Alaska
  • Alaska Women's Cancer Care โ€” Anchorage, Alaska
  • Anchorage Oncology Centre โ€” Anchorage, Alaska
  • Katmai Oncology Group โ€” Anchorage, Alaska
  • Providence Alaska Medical Center โ€” Anchorage, Alaska
  • CTCA at Western Regional Medical Center โ€” Goodyear, Arizona
  • Kingman Regional Medical Center โ€” Kingman, Arizona
  • Cancer Center at Saint Joseph's โ€” Phoenix, Arizona
  • Mayo Clinic Hospital in Arizona โ€” Phoenix, Arizona
  • Mayo Clinic in Arizona โ€” Scottsdale, Arizona
  • University of Arizona Cancer Center-Orange Grove Campus โ€” Tucson, Arizona
  • Banner University Medical Center - Tucson โ€” Tucson, Arizona
  • University of Arizona Cancer Center-North Campus โ€” Tucson, Arizona
  • Mercy Hospital Fort Smith โ€” Fort Smith, Arkansas
  • CHI Saint Vincent Cancer Center Hot Springs โ€” Hot Springs, Arkansas
  • Mission Hope Medical Oncology - Arroyo Grande โ€” Arroyo Grande, California
  • PCR Oncology โ€” Arroyo Grande, California
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center โ€” Burbank, California
  • UC San Diego Moores Cancer Center โ€” La Jolla, California
  • Providence Queen of The Valley โ€” Napa, California
  • Saint Joseph Hospital - Orange โ€” Orange, California
  • UC Irvine Health/Chao Family Comprehensive Cancer Center โ€” Orange, California

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—