International Validation Study of Sentinel Node Biopsy in Early Cervical Cancer (NCT03386734)
🩺 Plain-English Summary (8th-Grade Level)
SENTICOL III is large prospective multicenter international randomized study designed to validate the Sentinel Lymph Node (SLN) mapping technique in early cervical cancer. This "validation study" will compare the outcome of patients with negative SLN (experimental arm) vs patients with negative SLN + Pelvic Lymph Node dissection (PLN)(reference arm). There will be a "quality assurance" program which will be developed in participating centers with detailed requirements in terms of surgeons' qualifications, pathology qualification, SLN ultrastaging, standardization of the procedure, etc. as well as respect of the "safety algorithm".
Who can join: Review the eligibility criteria below.
Location: CHC MontLégia — Liège
Age range: 18 Years
🧪 Interventions in This Study
- SLN biopsy only (PROCEDURE)
- SLN biopsy + PLN dissection (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (106 Sites)
Showing the first 25 of 106 sites.
- CHC MontLégia — Liège,
- Hospital Erasto Gaertner — Curitiba, Paraná
- Barretos Cancer Hospital — Campo Grande,
- Brazilian National Cancer Institute — Rio de Janeiro,
- AC Camargo Cancer Center - Sao Paulo — São Paulo,
- Hospital Amaral Carvalho de Jaù — São Paulo,
- Hospital Israelita Albert Einstein — São Paulo,
- CIUSSS de l'Est-de-I'lle-de-Montreal Hopital Maisonneuve-Rosemont (CAHA) — Montreal,
- CHUM Centre Hospitalier de l'Université de Montréal — Montreal,
- CHU Québec (Hôtel Dieu) — Québec,
- Allan Blair Cancer Centre (CASA) — Regina,
- Saskatoon Cancer Centre.(CASS) — Saskatoon,
- CIUSS de l'Estrie - Centre hospitalier universitaire de Sherbrooke - CAGH — Sherbrooke,
- Clinical Research Unit at Vancouver Coastal Health Authority (CAVG) — Vancouver,
- CancerCare Manitoba — Winnipeg,
- Cancer Hospital of University of Chinese Academy of Science — Hangzhou, Zhejiang
- The 1st Affiliated Hospital — Wenzhou,
- University Hospital Olomouc — Olomouc,
- University Hospital Ostrava — Ostrava-Poruba,
- General University Hospital — Prague,
- University Hospital Bulovka — Prague,
- CHU de la Réunion — Saint-Denis, La Réunion
- Grand Hôpital de l'Est Francilien — Paris, Marne-le-Vallée
- CHU d'Amiens — Amiens,
- CHU de Besançon — Besançon,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.