๐๏ธ Verified NIH Record โข Updated 2026-04-07
A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004) (NCT03401788)
An Open-Label Phase 2 Study to Evaluate PT2977 for the Treatment of Von Hippel Lindau Disease-Associated Renal Cell Carcinoma
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
๐ฉบ Plain-English Summary (8th-Grade Level)
This study is designed to investigate belzutifan as a treatment for VHL disease associated RCC.
Who can join: Review the eligibility criteria below.
Location: National Institutes of Health Clinical Center โ Bethesda, Maryland
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (11 Sites)
- National Institutes of Health Clinical Center โ Bethesda, Maryland
- Massachusetts General Hospital โ Boston, Massachusetts
- University of Michigan โ Ann Arbor, Michigan
- University of Pennsylvania Medical Center โ Philadelphia, Pennsylvania
- University of Pittsburgh Medical Center โ Pittsburgh, Pennsylvania
- Vanderbilt Medical Center โ Nashville, Tennessee
- MD Anderson Cancer Center โ Houston, Texas
- Huntsman Cancer Institute โ Salt Lake City, Utah
- Aarhus University Hospital โ Aarhus,
- Hospital Georges Pompidou โ Paris,
- Cambridge University Hospital โ Cambridge,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All VHL - Von Hippel-Lindau Syndrome clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.