๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-23

A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine (NCT03432286)

A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Patients 6 to 17 Years of Age With Episodic Migraine - the REBUILD-1 Study

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main purpose of this study is to evaulate the efficacy and safety of galcanezumab in participants 6 to 17 years of age for the preventive treatment of episodic migraine. The primary objective is to demonstrate the superiority of galcanezumab versus placebo in the reduction of monthly migraine headache days across the 3-month double-blind treatment period.

Who can join: Review the eligibility criteria below.

Location: Rehabilitation & Neurological Services โ€” Huntsville, Alabama

Age range: 6 Years to 17 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (73 Sites)

Showing the first 25 of 73 sites.

  • Rehabilitation & Neurological Services โ€” Huntsville, Alabama
  • 21st Century Neurology, a Division of Xenoscience, Inc. โ€” Phoenix, Arizona
  • Phoenix Children's Hospital โ€” Phoenix, Arizona
  • Center for Neurosciences โ€” Tucson, Arizona
  • Miller Children's & Women's Hospital Long Beach โ€” Long Beach, California
  • Wr-McCr, Llc โ€” San Diego, California
  • Children's Hospital Colorado โ€” Aurora, Colorado
  • Clinical Neuroscience Solutions, Inc. dba CNS Healthcare โ€” Jacksonville, Florida
  • University of Miami Don Suffer Clinical Research Building โ€” Miami, Florida
  • Ezy Medical Research โ€” Miami Lakes, Florida
  • Clinical Neuroscience Solutions โ€” Orlando, Florida
  • Avanza Medical Research Center โ€” Pensacola, Florida
  • USF Health โ€” Tampa, Florida
  • Premiere Research Institute at Palm Beach Neurology โ€” West Palm Beach, Florida
  • Clinical Integrative Research Center of Atlanta, LLC โ€” Atlanta, Georgia
  • Meridian Clinical Research, LLC โ€” Savannah, Georgia
  • Medical Research Partners โ€” Ammon, Idaho
  • Elite Clinical Trials โ€” Blackfoot, Idaho
  • Northwest Clinical Trials โ€” Boise, Idaho
  • Inpatient Pharmacy โ€” Hoffman Estates, Illinois
  • University of Kentucky Chandler Medical Center โ€” Lexington, Kentucky
  • Pharmasite Research, Inc. โ€” Baltimore, Maryland
  • Boston Clinical Trials โ€” Boston, Massachusetts
  • MedVadis Research Corporation โ€” Waltham, Massachusetts
  • Minneapolis Clinic of Neurology - Burnsville Office โ€” Burnsville, Minnesota

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—