🏛️ Verified NIH Record • Updated 2025-03-11
Open-Label Study of AG10 in Patients with Cardiomyopathy (NCT03536767)
An Open-Label Extension and Safety Monitoring Study of Patients with Symptomatic Transthyretin Cardiomyopathy Who Have Completed the Phase II Study AG10-201
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Eidos Therapeutics, a BridgeBio company
🩺 Plain-English Summary (8th-Grade Level)
This prospective, multicenter open-label study will evaluate the long-term safety, tolerability, PK and PD of AG10 administered on a background of stable heart failure therapy.
Who can join: Review the eligibility criteria below.
Location: Stanford University — Palo Alto, California
Age range: 18 Years to 90 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Stanford University — Palo Alto, California
- University of California San Francisco — San Francisco, California
- Yale University — New Haven, Connecticut
- Northwestern University — Chicago, Illinois
- Brigham and Women's Hospital — Boston, Massachusetts
- Mayo Clinic — Rochester, Minnesota
- Columbia University — New York, New York
- Oregon Health & Science University — Portland, Oregon
- Medical University of South Carolina — Charleston, South Carolina
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Amyloid Cardiomyopathy
- Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy — London, Ontario
- Exercise Training in Transthyretin Cardiac Amyloidosis — Boston, Massachusetts
Explore by condition: All Amyloid Cardiomyopathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.