A Study Designed to Evaluate the Safety and Efficacy of Venetoclax Plus Dexamethasone (VenDex) Compared With Pomalidomide Plus Dexamethasone (PomDex) in Participants With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma. (NCT03539744)
A Phase 3, Multicenter, Randomized, Open Label Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Subjects With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma
๐ฉบ Plain-English Summary (8th-Grade Level)
A study designed tocompare progression-free survival (PFS) in participants with t(11;14)-positive MM treated with venetoclax in combination with dexamethasone versus pomalidomide in combination with dexamethasone.
Who can join: Review the eligibility criteria below.
Location: Duplicate_University of Arizona Cancer Center - North Campus /ID# 218407 โ Tucson, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (180 Sites)
Showing the first 25 of 180 sites.
- Duplicate_University of Arizona Cancer Center - North Campus /ID# 218407 โ Tucson, Arizona
- VA Central California Health Care System /ID# 200047 โ Fresno, California
- University of California, Los Angeles /ID# 171524 โ Los Angeles, California
- Rocky Mountain Regional VA Medical Center/Eastern Colorado Health Care System /ID# 222904 โ Aurora, Colorado
- Mayo Clinic /ID# 200075 โ Jacksonville, Florida
- Cleveland Clinic Florida /ID# 208884 โ Weston, Florida
- Duplicate_Norton Cancer Institute /ID# 200834 โ Louisville, Kentucky
- University of Maryland, Baltimore /ID# 217422 โ Baltimore, Maryland
- Boston Medical Center /ID# 223606 โ Boston, Massachusetts
- Barbara Ann Karmanos Cancer In /ID# 201377 โ Detroit, Michigan
- Duplicate_Henry Ford Hospital /ID# 171531 โ Detroit, Michigan
- Mayo Clinic - Rochester /ID# 201091 โ Rochester, Minnesota
- Columbia University Medical Center /ID# 200715 โ New York, New York
- Fairview Hospital - Moll Pavilion /ID# 208919 โ Cleveland, Ohio
- Cleveland Clinic Main Campus /ID# 202247 โ Cleveland, Ohio
- UPMC Hillman Cancer Ctr /ID# 200063 โ Pittsburgh, Pennsylvania
- MD Anderson Cancer Center at Texas Medical Center /ID# 200060 โ Houston, Texas
- Huntsman Cancer Institute /ID# 218406 โ Salt Lake City, Utah
- VA Puget Sound Health Care System /ID# 222708 โ Seattle, Washington
- Liverpool Hospital /ID# 202431 โ Liverpool, New South Wales
- Sydney Adventist Hospital /ID# 222874 โ Wahroonga, New South Wales
- Wollongong Hospital /ID# 205545 โ Wollongong, New South Wales
- ICON Cancer Care - Townsville /ID# 206565 โ Hyde Park, Queensland
- Icon Cancer Centre /ID# 205663 โ South Brisbane, Queensland
- The Queen Elizabeth Hospital /ID# 202432 โ Woodville South, South Australia
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma โ Birmingham, Alabama
- Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant โ Tampa, Florida
- MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb โ Beverly Hills, California
- A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma โ Phoenix, Arizona
- A Study of Carfilzomib, Lenalidomide, Vorinostat, and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma โ Hackensack, New Jersey
Explore by condition: All Multiple Myeloma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.