Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer (NCT03598257)
A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently With Radiotherapy Versus Radiotherapy Alone for Inflammatory Breast Cancer
🩺 Plain-English Summary (8th-Grade Level)
This phase II trial studies how well radiation therapy with or without olaparib works in treating patients with inflammatory breast cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep cancer cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. It is not yet known whether radiation therapy with or without olaparib may work better in treating patients with inflammatory breast cancer.
Who can join: Review the eligibility criteria below.
Location: Anchorage Associates in Radiation Medicine — Anchorage, Alaska
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (220 Sites)
Showing the first 25 of 220 sites.
- Anchorage Associates in Radiation Medicine — Anchorage, Alaska
- Alaska Oncology and Hematology LLC — Anchorage, Alaska
- Anchorage Oncology Centre — Anchorage, Alaska
- Katmai Oncology Group — Anchorage, Alaska
- Providence Alaska Medical Center — Anchorage, Alaska
- Banner MD Anderson Cancer Center — Gilbert, Arizona
- University of Arizona Cancer Center-Orange Grove Campus — Tucson, Arizona
- University of Arizona Cancer Center-North Campus — Tucson, Arizona
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas
- Alta Bates Summit Medical Center-Herrick Campus — Berkeley, California
- Epic Care Partners in Cancer Care — Emeryville, California
- Los Angeles General Medical Center — Los Angeles, California
- USC / Norris Comprehensive Cancer Center — Los Angeles, California
- Fremont - Rideout Cancer Center — Marysville, California
- Desert Regional Medical Center — Palm Springs, California
- Palo Alto Medical Foundation Health Care — Palo Alto, California
- University of California Davis Comprehensive Cancer Center — Sacramento, California
- Mission Hope Medical Oncology - Santa Maria — Santa Maria, California
- Gene Upshaw Memorial Tahoe Forest Cancer Center — Truckee, California
- Sutter Solano Medical Center/Cancer Center — Vallejo, California
- Penrose-Saint Francis Healthcare — Colorado Springs, Colorado
- AdventHealth Porter — Denver, Colorado
- Shaw Cancer Center — Edwards, Colorado
- AdventHealth Littleton — Littleton, Colorado
- AdventHealth Parker — Parker, Colorado
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Breast Inflammatory Carcinoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.