Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations (NCT03609216)
A Phase II Study of Gemcitabine Plus Cisplatin Chemotherapy in Patients With Muscle-invasive Bladder Cancer With Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations
🩺 Plain-English Summary (8th-Grade Level)
This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Who can join: Review the eligibility criteria below.
Location: Fairbanks Memorial Hospital — Fairbanks, Alaska
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (424 Sites)
Showing the first 25 of 424 sites.
- Fairbanks Memorial Hospital — Fairbanks, Alaska
- CTCA at Western Regional Medical Center — Goodyear, Arizona
- Cancer Center at Saint Joseph's — Phoenix, Arizona
- Mercy Hospital Fort Smith — Fort Smith, Arkansas
- CHI Saint Vincent Cancer Center Hot Springs — Hot Springs, Arkansas
- University of Arkansas for Medical Sciences — Little Rock, Arkansas
- Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California
- Mercy Cancer Center - Carmichael — Carmichael, California
- Mercy San Juan Medical Center — Carmichael, California
- Mercy Cancer Center - Elk Grove — Elk Grove, California
- Cedars Sinai Medical Center — Los Angeles, California
- Contra Costa Regional Medical Center — Martinez, California
- Fremont - Rideout Cancer Center — Marysville, California
- Mercy Cancer Center — Merced, California
- Mercy Cancer Center - Rocklin — Rocklin, California
- Mercy Cancer Center - Sacramento — Sacramento, California
- University of California Davis Comprehensive Cancer Center — Sacramento, California
- Pacific Central Coast Health Center-San Luis Obispo — San Luis Obispo, California
- Mission Hope Medical Oncology - Santa Maria — Santa Maria, California
- Saint Joseph's Medical Center — Stockton, California
- BASS Medical Group - Lennon — Walnut Creek, California
- Woodland Memorial Hospital — Woodland, California
- Rocky Mountain Cancer Centers-Aurora — Aurora, Colorado
- The Medical Center of Aurora — Aurora, Colorado
- Rocky Mountain Cancer Centers-Boulder — Boulder, Colorado
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Infiltrating Bladder Urothelial Carcinoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.