๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-17

Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer. (NCT03616587)

A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women With ER-positive, HER2-negative Advanced Breast Cancer (SERENA-1)

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Cancer (SERENA-1)

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Aurora, Colorado

Age range: 18 Years to 130 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (17 Sites)

  • Research Site โ€” Aurora, Colorado
  • Research Site โ€” Sarasota, Florida
  • Research Site โ€” Philadelphia, Pennsylvania
  • Research Site โ€” Nashville, Tennessee
  • Research Site โ€” Salt Lake City, Utah
  • Research Site โ€” Barcelona,
  • Research Site โ€” Barcelona,
  • Research Site โ€” Madrid,
  • Research Site โ€” Madrid,
  • Research Site โ€” Seville,
  • Research Site โ€” Valencia,
  • Research Site โ€” Cambridge,
  • Research Site โ€” Leeds,
  • Research Site โ€” London,
  • Research Site โ€” Manchester,
  • Research Site โ€” Sutton,
  • Research Site โ€” Sutton,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—