🏛️ Verified NIH Record • Updated 2026-01-28
CFI-400945 in Patients With Advanced/Metastatic Breast Cancer (NCT03624543)
A Phase II Study of CFI-400945 in Patients With Advanced/Metastatic Breast Cancer
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Canadian Cancer Trials Group
🩺 Plain-English Summary (8th-Grade Level)
The standard or usual treatment for this disease is to undergo chemotherapy to slow the spread of the disease and relieve some symptoms of cancer. Patients will have already had at least one chemotherapy treatment for their disease at this stage.
Who can join: Review the eligibility criteria below.
Location: Juravinski Cancer Centre at Hamilton Health Sciences — Hamilton, Ontario
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- Juravinski Cancer Centre at Hamilton Health Sciences — Hamilton, Ontario
- London Regional Cancer Program — London, Ontario
- Ottawa Hospital Research Institute — Ottawa, Ontario
- Odette Cancer Centre — Toronto, Ontario
- University Health Network — Toronto, Ontario
- Allan Blair Cancer Centre — Regina, Saskatchewan
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.