๐๏ธ Verified NIH Record โข Updated 2026-05-28
The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE (NCT03635788)
A Phase III Study to Evaluate Long-Acting Antiretroviral Therapy in Non-Adherent HIV-Infected Individuals
๐ต Active, Not Recruiting Phase3 ๐ Investigational Drug / Biologic Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study was to compare the efficacy, safety, and durability of two different strategies to treat participants with a history of sub-optimal adherence and control of their HIV infection: long-acting (LA) antiretroviral therapy (ART) and all-oral standard of care (SOC).
Who can join: Review the eligibility criteria below.
Location: Alabama CRS โ Birmingham, Alabama
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (33 Sites)
Showing the first 25 of 33 sites.
- Alabama CRS โ Birmingham, Alabama
- University of Southern California CRS โ Los Angeles, California
- UCLA CARE Center CRS โ Los Angeles, California
- UCSD Antiviral Research Center CRS โ San Diego, California
- Ucsf Hiv/Aids Crs โ San Francisco, California
- Harbor-UCLA CRS โ Torrance, California
- University of Colorado Hospital CRS โ Aurora, Colorado
- Univ. of Florida Jacksonville NICHD CRS โ Jacksonville, Florida
- The Ponce de Leon Center CRS โ Atlanta, Georgia
- Northwestern University CRS โ Chicago, Illinois
- Rush University CRS โ Chicago, Illinois
- Johns Hopkins University CRS โ Baltimore, Maryland
- Massachusetts General Hospital CRS (MGH CRS) โ Boston, Massachusetts
- Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS โ Boston, Massachusetts
- Washington University Therapeutics (WT) CRS โ St Louis, Missouri
- New Jersey Medical School Clinical Research Center CRS โ Newark, New Jersey
- Weill Cornell Chelsea CRS โ New York, New York
- Columbia P&S CRS โ New York, New York
- Weill Cornell Uptown CRS โ New York, New York
- SUNY Stony Brook NICHD CRS โ Stony Brook, New York
- Jacobi Med. Ctr. Bronx NICHD CRS โ The Bronx, New York
- Chapel Hill CRS โ Chapel Hill, North Carolina
- Greensboro CRS โ Greensboro, North Carolina
- Cincinnati Clinical Research Site โ Cincinnati, Ohio
- Case Clinical Research Site โ Cleveland, Ohio
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in HIV Infections
- Testing a Real-time Electronic Antiretroviral Adherence Monitoring Intervention โ Chicago, Illinois
- The Ganchero Intervention for Migrant People Who Inject Drugs From Puerto Rico in New York City โ New York, New York
- Efficacy, Safety and Tolerability Study of Long-acting Cabotegravir Plus Long-acting Rilpivirine (CAB LA + RPV LA) in Human-immunodeficiency Virus-1 (HIV-1) Infected Adults โ Birmingham, Alabama
- Clinical Decision Support for PrEP โ Los Angeles, California
- Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care โ Baltimore, Maryland
- A Study to Assess the Safety and Pharmacokinetics of a Human Monoclonal Antibody (VH4527079) in Healthy Adults and Persons With HIV โ Las Vegas, Nevada
Explore by condition: All HIV Infections clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.