ποΈ Verified NIH Record β’ Updated 2026-02-20
Olaparib + Sapacitabine in BRCA Mutant Breast Cancer (NCT03641755)
A Phase Ib/II Study of Olaparib With Sapacitabine in BRCA Mutant Breast Cancer
π΅ Active, Not Recruiting Phase1 π Investigational Drug / Biologic Sponsor: Dana-Farber Cancer Institute
π©Ί Plain-English Summary (8th-Grade Level)
This research study is studying a combination of drugs as a possible treatment for breast cancer with a BRCA mutation. The interventions involved in this study are: * Sapacitabine (CYC682) * Olaparib (Lynparzaβ’)
Who can join: Review the eligibility criteria below.
Location: Dana Farber Cancer Institute β Boston, Massachusetts
Age range: 18 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (2 Sites)
- Dana Farber Cancer Institute β Boston, Massachusetts
- Broad Institute of MIT β Cambridge, Massachusetts
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.