πŸ›οΈ Verified NIH Record β€’ Updated 2026-02-20

Olaparib + Sapacitabine in BRCA Mutant Breast Cancer (NCT03641755)

A Phase Ib/II Study of Olaparib With Sapacitabine in BRCA Mutant Breast Cancer

πŸ”΅ Active, Not Recruiting Phase1 πŸ’Š Investigational Drug / Biologic Sponsor: Dana-Farber Cancer Institute

🩺 Plain-English Summary (8th-Grade Level)

This research study is studying a combination of drugs as a possible treatment for breast cancer with a BRCA mutation. The interventions involved in this study are: * Sapacitabine (CYC682) * Olaparib (Lynparzaβ„’)

Who can join: Review the eligibility criteria below.

Location: Dana Farber Cancer Institute β€” Boston, Massachusetts

Age range: 18 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (2 Sites)

  • Dana Farber Cancer Institute β€” Boston, Massachusetts
  • Broad Institute of MIT β€” Cambridge, Massachusetts

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Breast Cancer clinical trials

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—