Intravenous Estrogen in Kidney Transplant Study (NCT03663543)
The Use of Peri-Operative Intravenous Estrogen for the Mitigation of Ischemia Reperfusion Injury in the Setting of Renal Transplantation
๐ฉบ Plain-English Summary (8th-Grade Level)
Ischemia perfusion injury (IRI) is a major cause of organ injury during kidney transplantation. Currently there are no treatments for IRI other than dialysis. Preliminary studies in female mice have found protection from IRI when given short term estrogen supplements. This study will look at the effect of intravenous estrogen given peri-operatively to reduce the effect of IRI in female kidney transplant recipients.
Who can join: Review the eligibility criteria below.
Location: University of Pennsylvania โ Philadelphia, Pennsylvania
Age range: 21 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- University of Pennsylvania โ Philadelphia, Pennsylvania
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ischemia Reperfusion Injury
- NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial โ San Francisco, California
- Safety and Efficacy of Treprostinil (Remodulinยฎ) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation โ Providence, Rhode Island
Explore by condition: All Ischemia Reperfusion Injury clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.