Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (NCT03674307)
Canadian-Australasian Randomised Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease
🩺 Plain-English Summary (8th-Grade Level)
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major Adverse Cardiac Events. Secondary analyses will assess the impact of screening on the rate of transplantation, and the relative cost-effectiveness of screening.
Who can join: Review the eligibility criteria below.
Location: University of Arizona — Tucson, Arizona
Age range: 18 Years
🧪 Interventions in This Study
- No screening (OTHER)
- Regular Screening (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (22 Sites)
- University of Arizona — Tucson, Arizona
- The George Washington University — Washington D.C., District of Columbia
- University of Alberta — Edmonton, Alberta
- University of British Columbia — Vancouver, British Columbia
- Dalhousie University — Halifax, Nova Scotia
- St. Joseph's Healthcare — Hamilton, Ontario
- Kingston Health Science Centre — Kingston, Ontario
- London Health Science Centre — London, Ontario
- The Ottawa Hospital Research Institute — Ottawa, Ontario
- University Health Network — Toronto, Ontario
- St Michael's Hospital — Toronto, Ontario
- CHU de Quebec-Universite Laval's L'Hotel-Dieu de Quebec — Laval, Quebec
- University of Montreal, Maisonneuve-Rosemont Hospital — Montreal, Quebec
- McGill University Health Centre — Montreal, Quebec
- Universite de Montreal, Hopital Maisonneuve-Rosemont — Montreal, Quebec
- St. Paul's Hospital, University of Saskatchewan — Saskatoon, Saskatchewan
- Charité Universitätsmedizin — Berlin,
- Sussex Brighton R&D — Brighton,
- King's College Hospital NHS Foundation Trust — Brixton,
- Epsom and St Helier University Hospitals NHS Trust — Carshalton,
- Barts Health NHS Trust — London,
- St George's University Hospital NHS Trust Foundation — London,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.