๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-01-07

Multi-Center Study of GSK2857916 in Combination With Pomalidomide and Dex (NCT03715478)

A Phase 1/2 Multi-Center, Open Label, Dose Escalation Study to Determine the RP2D, Safety and Efficacy of GSK2857916 in Combination With Pomalidomide and Low-Dose Dexamethasone in Subjects With Relapsed and/or Refractory Multiple Myeloma

๐Ÿ”ต Active, Not Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Canadian Myeloma Research Group

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a Phase 1/2, multi-centre, single-arm, open-label, dose-escalation study that will evaluate the safety and efficacy of IV GSK2857916 in combination with PO pomalidomide and low-dose PO dexamethasone in subjects with relapsed and/or refractory MM.

Who can join: Review the eligibility criteria below.

Location: Cross Cancer Institute โ€” Edmonton, Alberta

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (9 Sites)

  • Cross Cancer Institute โ€” Edmonton, Alberta
  • Vancouver General Hospital โ€” Vancouver, British Columbia
  • CancerCare Manitoba โ€” Winnipeg, Manitoba
  • QEII Health Sciences Centre โ€” Halifax, Nova Scotia
  • Juravinski Cancer Centre โ€” Hamilton, Ontario
  • London Health Sciences Centre โ€” London, Ontario
  • The Ottawa Hospital โ€” Ottawa, Ontario
  • Princess Margaret Cancer Centre โ€” Toronto, Ontario
  • Allan Blair Cancer Centre โ€” Regina, Saskatchewan

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Relapsed and/or Refractory Multiple Myeloma

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—