🏛️ Verified NIH Record • Updated 2026-03-13
A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD (NCT03734237)
🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine
🩺 Plain-English Summary (8th-Grade Level)
A total of 18,000 eligible subjects (or 6,000 subject distributed evenly between the 3 study arms) will be enrolled. Eligible subjects will be randomized in 1:1:1 (cell-culture-based vaccine, the recombinant vaccine, or the egg-based vaccine) over four influenza seasons (2018-2019, 2019-2020, 2020-2021, and 2021-2022).
Who can join: Review the eligibility criteria below.
Location: Naval Medical Center San Diego — San Diego, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Naval Medical Center San Diego — San Diego, California
- United States Naval Academy — Annapolis, Maryland
- USU — Bethesda, Maryland
- Walter Reed National Military Medical Center — Bethesda, Maryland
- Womack Army Medical Center — Fort Bragg, North Carolina
- Brooke Army Medical Center — Fort Sam Houston, Texas
- Lackland Airforce Base — San Antonio, Texas
- Naval Medical Center Portsmouth — Portsmouth, Virginia
- Madigan Army Medical Center — Tacoma, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Influenza
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- Phase 1/2 Study of a Plant-Based Seasonal Recombinant Trivalent VLP Influenza Vaccine — Halifax, Nova Scotia
- B Cell and Antibody Response to Seasonal Influenza Vaccines in Younger and Older Adults — Birmingham, Alabama
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza — Anniston, Alabama
- Influenza IMPRINT Cohort: Defining the Impact of Initial Influenza Exposure on Immunity in Infants — Cincinnati, Ohio
- A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults — San Bernardino, California
Explore by condition: All Influenza clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.