๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-17

Trimodality Therapy With/Out Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer (NCT03768570)

A Randomized Phase II Trial Assessing Trimodality Therapy With or Without Adjuvant Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Canadian Cancer Trials Group

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to find out what effects durvalumab has on bladder cancer, combined with treatment after completion of surgery, chemotherapy and radiotherapy.

Who can join: Review the eligibility criteria below.

Location: Tom Baker Cancer Centre โ€” Calgary, Alberta

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (31 Sites)

Showing the first 25 of 31 sites.

  • Tom Baker Cancer Centre โ€” Calgary, Alberta
  • Cross Cancer Institute โ€” Edmonton, Alberta
  • BCCA - Vancouver Cancer Centre โ€” Vancouver, British Columbia
  • Health Sciences North โ€” Greater Sudbury, Ontario
  • Juravinski Cancer Centre at Hamilton Health Sciences โ€” Hamilton, Ontario
  • Kingston Health Sciences Centre โ€” Kingston, Ontario
  • London Regional Cancer Program โ€” London, Ontario
  • Stronach Regional Health Centre at Southlake โ€” Newmarket, Ontario
  • Ottawa Hospital Research Institute โ€” Ottawa, Ontario
  • Thunder Bay Regional Health Sciences Centre/ โ€” Thunder Bay, Ontario
  • University Health Network โ€” Toronto, Ontario
  • The Jewish General Hospital โ€” Montreal, Quebec
  • The Research Institute of the McGill University โ€” Montreal, Quebec
  • Allan Blair Cancer Centre โ€” Regina, Saskatchewan
  • Saskatoon Cancer Centre โ€” Saskatoon, Saskatchewan
  • Hospital Clinic i Provincial โ€” Barcelona,
  • Hospital de la Santa Creu i Sant Pau โ€” Barcelona,
  • Hospital Clinico San Carlos โ€” Madrid,
  • Hospital 12 de Octubre โ€” Madrid,
  • Hospital Universitario La Paz โ€” Madrid,
  • Hospital Madrid Norte Sanchinarro โ€” Madrid,
  • Hospital Universitario Marques de Valdecilla โ€” Santander,
  • Instituto Valenciano de Oncologia โ€” Valencia,
  • Royal Devon and Exeter Hospital โ€” Exeter, Devon
  • Royal Cornwall Hospitals NHS Trust โ€” Cornwall, England

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Bladder Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—