Osimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib (NCT03778229)
A Phase II Study Assessing the Efficacy of Osimertinib in Combination With Savolitinib in Patients With EGFRm+ and MET+, Locally Advanced or Metastatic Non Small Cell Lung Cancer Who Have Progressed Following Treatment With Osimertinib.
🩺 Plain-English Summary (8th-Grade Level)
This study (the SAVANNAH study) will investigate the efficacy of osimertinib in combination with savolitinib in patients with EGFRm+ and MET+, locally advanced or metastatic NSCLC who have progressed following treatment with osimertinib
Who can join: Review the eligibility criteria below.
Location: Research Site — La Jolla, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (90 Sites)
Showing the first 25 of 90 sites.
- Research Site — La Jolla, California
- Research Site — Los Angeles, California
- Research Site — Sacramento, California
- Research Site — Washington D.C., District of Columbia
- Research Site — Baltimore, Maryland
- Research Site — Boston, Massachusetts
- Research Site — Rochester, Minnesota
- Research Site — Brooklyn, New York
- Research Site — Philadelphia, Pennsylvania
- Research Site — Pittsburgh, Pennsylvania
- Research Site — Seattle, Washington
- Research Site — Barretos,
- Research Site — Curitiba,
- Research Site — Goiânia,
- Research Site — Porto Alegre,
- Research Site — Porto Alegre,
- Research Site — Rio de Janeiro,
- Research Site — Salvador,
- Research Site — São José do Rio Preto,
- Research Site — São Paulo,
- Research Site — São Paulo,
- Research Site — Calgary, Alberta
- Research Site — Edmonton, Alberta
- Research Site — Newmarket, Ontario
- Research Site — North York, Ontario
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.