A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes (NCT03811561)
Long-term Effects of Semaglutide on Diabetic Retinopathy in Subjects With Type 2 Diabetes
🩺 Plain-English Summary (8th-Grade Level)
This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get semaglutide or placebo in addition to their diabetes medicines - which treatment the participant gets is decided by chance. Participants will inject the study medicine using a pen-injector. The medicine must be injected in a skin fold in the stomach, thigh or upper arm once a week. The study will last for 5 years.
Who can join: Review the eligibility criteria below.
Location: Synexus Rsch /Cnt Phnx Med C — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (229 Sites)
Showing the first 25 of 229 sites.
- Synexus Rsch /Cnt Phnx Med C — Phoenix, Arizona
- Del Sol Research Management, LLC — Tucson, Arizona
- South Arizona VA Healthcare System — Tucson, Arizona
- Synexus Cln Rsrch Inc - Orange Gro FP — Tucson, Arizona
- Southern California Res Ctr — Coronado, California
- FDRC — Costa Mesa, California
- Advanced Investigative Medicine, Inc. — Hawthorne, California
- Diabetes/Lipid Mgmt & Res Ctr — Huntington Beach, California
- Scripps Whittier Diabetes Inst — La Jolla, California
- Torrance Clin Res Inst, Inc. — Lomita, California
- Angel City Research, Inc. — Los Angeles, California
- Downtown LA Res Ctr. Inc. — Los Angeles, California
- Riverside University Health System Medical Center — Moreno Valley, California
- Rancho Cucamonga Clinical Research — Rancho Cucamonga, California
- Clinical Trials Research_Sacramento_0 — Sacramento, California
- UCLA Diabetes Center at Santa Monica — Santa Monica, California
- Coastal Metabolic Research Center — Ventura, California
- Diablo Clinical Research, Inc. — Walnut Creek, California
- Barbara Davis Center — Aurora, Colorado
- Rocky Mount Reg VA Med-DN — Aurora, Colorado
- Chase Medical Research LLC — Waterbury, Connecticut
- Innovative Research of W FL — Clearwater, Florida
- Est Cst Inst for Rsrch,Jksnvil — Jacksonville, Florida
- Reyes Clinical Research, Inc — Miami, Florida
- Renstar Medical Research — Ocala, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.