A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors (NCT03872947)
A Phase 1b, Multicenter Study to Determine the Dose, Safety, Efficacy and Pharmacokinetics of TRK-950 When Used in Combinations With Selected Anti-Cancer Treatment Regimens in Patients With Selected Advanced Solid Tumors
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to establish the safety and the recommended dose of TRK-950 in combination with FOLFIRI, Gemcitabine / Cisplatin, Gemcitabine / Carboplatin, Ramucirumab / Paclitaxel, PD1 inhibitors (Nivolumab or Pembrolizumab), and Imiquimod Cream, Bevacizumab, Gemcitabine / Carboplatin / Bevacizumab, Pegylated liposomal doxorubicin (PLD), Carboplatin / PLD / Bevacizumab and Paclitaxel for selected advanced solid tumors.
Who can join: Review the eligibility criteria below.
Location: HonorHealth Research Institute — Scottsdale, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (14 Sites)
- HonorHealth Research Institute — Scottsdale, Arizona
- AOA-HOPE — Tucson, Arizona
- USC Norris Comprehensive Cancer Center — Los Angeles, California
- HOAG Memorial Hospital Presbyterian — Newport, California
- Ochsner Clinic Foundation — New Orleans, Louisiana
- Atlantic Health System — Morristown, New Jersey
- Perlmutter Cancer Center at NYU Langone — New York, New York
- Oncology Associates of Oregon, P.C.(Willamette Valley Cancer Institute and Research Center) — Eugene, Oregon
- Northwest Cancer Specialists — Portland, Oregon
- Texas Oncology, P.A. Baylor Charles A. Sammons Cancer Center — Dallas, Texas
- Texas Oncology - Downtown Fort Worth Cancer Center — Fort Worth, Texas
- Virginia Cancer Specialists, PC — Leesburg, Virginia
- Medical College of Wisconsin — Milwaukee, Wisconsin
- Centre Léon Bérard — Lyon,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Solid Tumor clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.