🏛️ Verified NIH Record • Updated 2026-01-29

Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS (NCT03905707)

A Double-Blind Phase 3 Extension Trial Assessing the Long Term Safety and Efficacy of Glepaglutide in Patients With Short Bowel Syndrome (SBS)

🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Zealand Pharma

🩺 Plain-English Summary (8th-Grade Level)

The primary objective of the trial is to evaluate the long-term safety of glepaglutide treatment in patients with short bowel syndrome (SBS). Glepaglutide is the International Nonproprietary Name and USAN for ZP1848.

Who can join: Review the eligibility criteria below.

Location: Georgetown University Medical Center — Washington D.C., District of Columbia

Age range: 18 Years to 90 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (27 Sites)

Showing the first 25 of 27 sites.

  • Georgetown University Medical Center — Washington D.C., District of Columbia
  • University of Chicago Children's Hospital — Chicago, Illinois
  • Mayo Clinic College of Medicine — Rochester, Minnesota
  • University of Nebraska Medical Center — Omaha, Nebraska
  • Mount Sinai Hospital — New York, New York
  • Cleveland Clinic — Cleveland, Ohio
  • Vanderbilt University Medical Center, Nashville — Nashville, Tennessee
  • UZ Leuven — Leuven,
  • The Royal Alexandra Hospital — Edmonton,
  • Western University — London,
  • University Health Network - Toronto General Hospital — Toronto,
  • Rigshospitalet — Copenhagen,
  • Hôpital Beaujon — Clichy,
  • Centre Hospitalier Lyon-Sud — Pierre-Bénite,
  • Charité - Universitätsmedizin Berlin — Berlin,
  • Universitätsklinikum Bonn — Bonn,
  • Universitätsklinikum Frankfurt - Med. Klinik I — Frankfurt,
  • Asklepios Kliniken Hamburg GmbH — Hamburg,
  • Universitätsmedizin Rostock — Rostock,
  • UMC Radboud Nijmegen — Nijmegen,
  • Wojewodzki Specjalistyczny Szpital im. M. Pirogowa w Lodzi — Lodz,
  • Solumed — Poznan,
  • Szpital Skawina sp. z o.o. im. Stanley Dudricka — Skawina,
  • St Mark's Hospital — Harrow,
  • UCLH Foundation NHS Trust — London,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗