The Role of Cerebellum in Speech (NCT03972202)
๐ฉบ Plain-English Summary (8th-Grade Level)
This study will investigate the how the cerebellum is involved in speech motor learning over time and short-term corrections in patients with cerebellar ataxia and healthy controls. This will be accomplished through three approaches: behavioral studies, magnetic resonance imaging (MRI), and transcranial magnetic stimulation (TMS). During behavioral studies, participants will be asked to speak into a microphone while their voice is played back over earphones, and to do other speaking tasks. MRI will be acquired to perform a detailed analysis on brain function and anatomy related to speech and the cerebellum. In healthy controls, TMS will also be performed to temporarily disrupt the cerebellum before, during, or after the participant performs speaking tasks. Patients with cerebellar ataxia and healthy volunteers will be asked to complete behavioral studies and/or MRI; healthy volunteers may be asked to additionally participate in TMS.
Who can join: Review the eligibility criteria below.
Location: University of California, Berkeley โ Berkeley, California
Age range: 18 Years to 75 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (3 Sites)
- University of California, Berkeley โ Berkeley, California
- University of California, San Francisco โ San Francisco, California
- University of Wisconsin--Madison โ Madison, Wisconsin
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cerebellar Ataxia
- Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex โ Elkins Park, Pennsylvania
- Individualized Neuro-Modulation Paired With Cerebellar Therapy โ Baltimore, Maryland
- Retraining Reaching in Cerebellar Ataxia โ Baltimore, Maryland
Explore by condition: All Cerebellar Ataxia clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.