๐๏ธ Verified NIH Record โข Updated 2026-05-01
Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial (NCT03990896)
๐ข Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Massachusetts General Hospital
๐ฉบ Plain-English Summary (8th-Grade Level)
This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 or BRCA 2 mutation.
Who can join: Review the eligibility criteria below.
Location: UCSF Medical Center-Mission Bay/Benioff Children's Hospital โ San Francisco, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (7 Sites)
- UCSF Medical Center-Mission Bay/Benioff Children's Hospital โ San Francisco, California
- Emory University Winship Cancer Institute โ Atlanta, Georgia
- Northwestern University โ Chicago, Illinois
- Massachusetts General Hospital Cancer Center โ Boston, Massachusetts
- Weill Cornell Medicine โ New York, New York
- Vanderbilt University โ Nashville, Tennessee
- MD Anderson Cancer Center โ Houston, Texas
๐ Contact the Study Coordinator
Phone: (617) 724-4000
Email: nvidula@mgh.harvard.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.