🏛️ Verified NIH Record • Updated 2026-01-29
Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease (NCT04005976)
🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: The University of Texas Health Science Center, Houston
🩺 Plain-English Summary (8th-Grade Level)
The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.
Who can join: Review the eligibility criteria below.
Location: HOAG memorial hospital presbyterian — Newport Beach, California
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (20 Sites)
- HOAG memorial hospital presbyterian — Newport Beach, California
- Hoag Memorial Hospital Presbyterian — Newport Beach, California
- Sutter Health — Sacramento, California
- University of Kentucky — Lexington, Kentucky
- Massachusetts General Hospital — Boston, Massachusetts
- University of Michigan — Ann Arbor, Michigan
- Washington University in St. Louis — St Louis, Missouri
- University of Nebraska Medical Center — Omaha, Nebraska
- St. Francis Hospital (Catholic Health) — Roslyn, New York
- Oregon Health & Science University — Portland, Oregon
- Baylor College of Medicine — Houston, Texas
- Texas Children's Hospital — Houston, Texas
- The University of Texas Health Science Center at Houston — Houston, Texas
- Inova Health System — Falls Church, Virginia
- University of Sydney — Sydney, New South Wales
- Ghent University Hospital (UZ Gent) — Ghent, East Flanders
- Foothills Medical Centre / Alberta Health Services — Calgary, Alberta
- Toronto General Hospital (UHN) — Toronto, Ontario
- Hospital Universitari Vall d'Hebron — Barcelona, Catalonia
- Great Ormond Street Hospital — London, England
📞 Contact the Study Coordinator
Phone: (713) 500-6725
Email: Dianna.M.Milewicz@uth.tmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.