Impact of Insomnia Treatment on Brain Responses During Resting-state and Cognitive Tasks (NCT04024787)
Neural Responses and Connectivity During Rest, Memory Encoding and Emotional Stimulation in Chronic Insomnia, and Their Relationships With Insomnia Treatment: a Wait-list Controlled Randomized Trial of Cognitive-behavioural Therapy for Insomnia
🩺 Plain-English Summary (8th-Grade Level)
Individuals with chronic insomnia have persistent difficulty falling and staying asleep, as well as complaints of altered daytime functioning that may be associated with cognitive impairments. The neural processes underlying these daytime complaints may involve abnormal activation of brain regions and neural networks involved in working memory, memory encoding and emotions. The goal of this study is to assess whether a psychological treatment for insomnia will reverse these abnormalities in brain responses to cognitive tasks and at rest. A secondary objective of the study is to characterize impairments in attentional processing and assess if the impairments can be reversed by the psychological treatment. We hypothesized that the psychological treatment for insomnia will lead to a normalization of the brain responses to working memory, declarative memory encoding, insomnia-related stimuli, and the functional connectivity within the default-mode and limbic networks.
Who can join: Review the eligibility criteria below.
Location: Perform Center, Concordia University — Montreal, Quebec
Age range: 25 Years to 65 Years
🧪 Interventions in This Study
- Cognitive-Behavioural therapy for insomnia (CBT-I) (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Perform Center, Concordia University — Montreal, Quebec
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Insomnia Behavioral Intervention Study — Philadelphia, Pennsylvania
- Lemborexant vs Zopiclone vs Clonidine for Insomnia Treatment in Chronic Pain Patients — Surrey, British Columbia
- Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0 — Durham, North Carolina
Explore by condition: All Chronic Insomnia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.