πŸ›οΈ Verified NIH Record β€’ Updated 2026-08-06

A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer (NCT04025879)

A Phase 3, Randomized, Double-blind Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Resection and Adjuvant Treatment With Nivolumab or Placebo for Participants With Resectable Stage II-IIIB Non-small Cell Lung Cancer

πŸ”΅ Active, Not Recruiting Phase3 πŸ’Š Investigational Drug / Biologic Sponsor: Bristol-Myers Squibb

🩺 Plain-English Summary (8th-Grade Level)

The main purpose of the study is to examine if periadjuvant (neoadjuvant, then adjuvant) immunotherapy will prolong event free survival in participants with early stage non-small cell lung cancer.

Who can join: Review the eligibility criteria below.

Location: Local Institution - 0104 β€” Tampa, Florida

Age range: 18 Years

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (108 Sites)

Showing the first 25 of 108 sites.

  • Local Institution - 0104 β€” Tampa, Florida
  • Local Institution - 0040 β€” Atlanta, Georgia
  • Local Institution - 0120 β€” Augusta, Georgia
  • Local Institution - 0145 β€” Chicago, Illinois
  • Local Institution - 0078 β€” Chicago, Illinois
  • Local Institution - 0121 β€” Orland Park, Illinois
  • Rcca Md Llc β€” Bethesda, Maryland
  • Local Institution - 0076 β€” Boston, Massachusetts
  • Local Institution - 0074 β€” Newton, Massachusetts
  • Local Institution - 0086 β€” Traverse City, Michigan
  • Local Institution - 0100 β€” Lebanon, New Hampshire
  • Local Institution - 0055 β€” Cincinnati, Ohio
  • Local Institution - 0102 β€” Cleveland, Ohio
  • Local Institution - 0054 β€” Houston, Texas
  • Local Institution - 0103 β€” Fredericksburg, Virginia
  • Local Institution - 0043 β€” Buenos Aires, Buenos Aires
  • Local Institution - 0032 β€” Ciudad Autonoma Beunos Aires, Buenos Aires
  • Local Institution - 0031 β€” ABB, Buenos Aires F.D.
  • Local Institution - 0030 β€” CABA,
  • Local Institution - 0020 β€” Sydney, New South Wales
  • Local Institution - 0033 β€” Heidelberg, Victoria
  • Local Institution - 0122 β€” Melbourne, Victoria
  • Local Institution - 0023 β€” North Ballarat, Victoria
  • Local Institution - 0002 β€” Edegem,
  • Local Institution - 0005 β€” LiΓ¨ge,

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—