🏛️ Verified NIH Record • Updated 2025-10-08
Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers (NCT04036305)
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Vanderbilt University Medical Center
🩺 Plain-English Summary (8th-Grade Level)
Local anesthetic resistance is commonly reported by patients with EDS. However, there are no objective data on the occurrence of local anesthetic resistance in EDS patients and in healthy volunteers. We propose to collect such objective data on the frequency of drug resistance and whether any problems with local anesthesia are due to initial ineffectiveness or due to its effects dissipating too soon.
Who can join: Review the eligibility criteria below.
Location: Vanderbilt University Medical Center — Nashville, Tennessee
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Vanderbilt University Medical Center — Nashville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ehlers-Danlos Syndrome
- Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers — Calgary, Alberta
- The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients — New Orleans, Louisiana
Explore by condition: All Ehlers-Danlos Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.