Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis (NCT04036435)
An Open-Label, Multi-Center Extension Study to Characterize the Long-Term Safety and Efficacy of BMS-986165 in Subjects With Moderate-to-Severe Plaque Psoriasis
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to evaluate the long-term safety and efficacy of the drug Deucravacitinib (BMS-986165) in participants who have been previously enrolled in an applicable Phase 3 psoriasis study. In addition, the study includes a vaccine cohort to evaluate whether deucravacitinib impacts the humoral immune response to 2 non-live vaccines, the Pneumovax 23 vaccine (pneumococcus), a T-cell independent vaccine, and the Boostrix vaccine (tetanus toxoid), a T-cell dependent vaccine. Additionally, this vaccine cohort assesses the safety of administering these vaccines to subjects with psoriasis receiving deucravacitinib compared to those receiving a placebo.
Who can join: Review the eligibility criteria below.
Location: Total Skin and Beauty Dermatology Center — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (302 Sites)
Showing the first 25 of 302 sites.
- Total Skin and Beauty Dermatology Center — Birmingham, Alabama
- Local Institution - 0278 — Birmingham, Alabama
- Alliance Dermatology and Mohs Center - Phoenix — Phoenix, Arizona
- Arizona Research Center — Phoenix, Arizona
- Synexus - Orange Grove Family Practice — Tucson, Arizona
- Johnson Dermatology — Fort Smith, Arkansas
- Burke Pharmaceutical Research — Hot Springs, Arkansas
- Northwest Arkansas Clinical Trials Center, PLLC — Rogers, Arkansas
- Local Institution - 0046 — Fountain Valley, California
- Local Institution - 0206 — Fresno, California
- Local Institution - 0017 — Irvine, California
- Interspond - Long Beach Clinical Trials — Long Beach, California
- Dermatology Research Associates - Los Angeles — Los Angeles, California
- Local Institution - 0236 — Los Angeles, California
- University of California San Diego Health Systems — San Diego, California
- Therapeutics Clinical Research — San Diego, California
- University Dermatology Group — San Diego, California
- Local Institution - 0094 — San Luis Obispo, California
- Clinical Science Institute — Santa Monica, California
- NorthBay Clinical Research — Santa Rosa, California
- Synexus - Santa Rosa — Santa Rosa, California
- Local Institution - 0042 — Sherman Oaks, California
- Care Access Research - Walnut Creek — Walnut Creek, California
- New England Research Associates — Bridgeport, Connecticut
- Stamford Therapeutics Consortium — Stamford, Connecticut
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Psoriasis
- Deucravacitinib Adherence Study — Winston-Salem, North Carolina
- An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects — San Diego, California
- Psoriasis Longitudinal Assessment and Registry — Birmingham, Alabama
- Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977 — Birmingham, Alabama
- Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis — Scottsdale, Arizona
Explore by condition: All Psoriasis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.