Targeted Plasticity Therapy for Posttraumatic Stress Disorder (NCT04064762)
🩺 Plain-English Summary (8th-Grade Level)
Posttraumatic stress disorder is a debilitating condition that develops in the aftermath of a traumatic experience, leading to hyperarousal, heightened anxiety, and uncontrolled fear that can be driven by intrusive memories or trauma reminders. The Texas Biomedical Device Center has developed a novel technique, termed targeted plasticity therapy (TPT), to boost neuroplasticity in conjunction with various forms of rehabilitation, including prolonged exposure therapy. The technique involves stimulation of the vagus nerve. The purpose of this open-label pilot study is to assess the safety of using a new device to deliver vagus nerve stimulation to reduce symptom severity in participants with PTSD when paired with prolonged exposure therapy. Additionally, the study will assess the prospective benefit of the system and garner an initial estimate of efficacy for a subsequent trial.
Who can join: Review the eligibility criteria below.
Location: Baylor University Medical Center — Dallas, Texas
Age range: 18 Years to 64 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Baylor University Medical Center — Dallas, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Post Traumatic Stress Disorder
- A Study of Psilocybin for PTSD — Baltimore, Maryland
- RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault — Québec, Quebec
- Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder — New York, New York
- TMS-fNIRS Personalized Dosing — Tallahassee, Florida
- NightWare and Cardiovascular Health in Women With PTSD — Aurora, Colorado
Explore by condition: All Post Traumatic Stress Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.