๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-11-18

Induction of Gut Permeability by an Oral Vaccine (NCT04083950)

๐Ÿ”ต Active, Not Recruiting Early Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: USDA, Western Human Nutrition Research Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study evaluates the effect of an oral typhoid vaccine on disruption of the intestinal barrier and response of the immune system. Intestinal and whole-body responses will be measured in all participants before and after the vaccine.

Who can join: Review the eligibility criteria below.

Location: USDA, ARS, Western Human Nutrition Research Center โ€” Davis, California

Age range: 18 Years to 49 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • USDA, ARS, Western Human Nutrition Research Center โ€” Davis, California

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—