๐๏ธ Verified NIH Record โข Updated 2026-07-02
A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma (NCT04133636)
68284528MMY2003: A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the overall minimal residual disease (MRD) negative rate of participants who receive JNJ-68284528.
Who can join: Review the eligibility criteria below.
Location: University Of California San Diego โ San Diego, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (47 Sites)
Showing the first 25 of 47 sites.
- University Of California San Diego โ San Diego, California
- University of California San Francisco โ San Francisco, California
- Yale University School Of Medicine โ New Haven, Connecticut
- Moffitt Cancer Center โ Tampa, Florida
- Emory University โ Atlanta, Georgia
- Northwestern University โ Chicago, Illinois
- University of Chicago โ Chicago, Illinois
- Indiana University โ Indianapolis, Indiana
- University of Iowa Hospitals and Clinics โ Iowa City, Iowa
- University of Kansas Cancer Center โ Westwood, Kansas
- Norton Cancer Institute โ Louisville, Kentucky
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Barbara Ann Karmanos Cancer Institute โ Detroit, Michigan
- Mayo Clinic Rochester โ Rochester, Minnesota
- Washington University School Of Medicine โ St Louis, Missouri
- Hackensack University Medical Center โ Hackensack, New Jersey
- Rutgers Cancer Institute of New Jersey โ New Brunswick, New Jersey
- Roswell Park Cancer Institute โ Buffalo, New York
- Mount Sinai Medical Center โ New York, New York
- Memorial Sloan-Kettering Cancer Center โ New York, New York
- Montefiore Medical Center โ The Bronx, New York
- Levine Cancer Institute, Carolinas HealthCare System โ Charlotte, North Carolina
- Cleveland Clinic โ Cleveland, Ohio
- Oregon Health And Science University โ Portland, Oregon
- University of Pennsylvania โ Philadelphia, Pennsylvania
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Multiple Myeloma
- Ixazomib + Pomalidomide + Dexamethasone In MM โ Boston, Massachusetts
- A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma โ Birmingham, Alabama
- Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant โ Tampa, Florida
- MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb โ Beverly Hills, California
- A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma โ Phoenix, Arizona
- A Study of Carfilzomib, Lenalidomide, Vorinostat, and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma โ Hackensack, New Jersey
Explore by condition: All Multiple Myeloma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.