๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-02

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma (NCT04133636)

68284528MMY2003: A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the overall minimal residual disease (MRD) negative rate of participants who receive JNJ-68284528.

Who can join: Review the eligibility criteria below.

Location: University Of California San Diego โ€” San Diego, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (47 Sites)

Showing the first 25 of 47 sites.

  • University Of California San Diego โ€” San Diego, California
  • University of California San Francisco โ€” San Francisco, California
  • Yale University School Of Medicine โ€” New Haven, Connecticut
  • Moffitt Cancer Center โ€” Tampa, Florida
  • Emory University โ€” Atlanta, Georgia
  • Northwestern University โ€” Chicago, Illinois
  • University of Chicago โ€” Chicago, Illinois
  • Indiana University โ€” Indianapolis, Indiana
  • University of Iowa Hospitals and Clinics โ€” Iowa City, Iowa
  • University of Kansas Cancer Center โ€” Westwood, Kansas
  • Norton Cancer Institute โ€” Louisville, Kentucky
  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • Barbara Ann Karmanos Cancer Institute โ€” Detroit, Michigan
  • Mayo Clinic Rochester โ€” Rochester, Minnesota
  • Washington University School Of Medicine โ€” St Louis, Missouri
  • Hackensack University Medical Center โ€” Hackensack, New Jersey
  • Rutgers Cancer Institute of New Jersey โ€” New Brunswick, New Jersey
  • Roswell Park Cancer Institute โ€” Buffalo, New York
  • Mount Sinai Medical Center โ€” New York, New York
  • Memorial Sloan-Kettering Cancer Center โ€” New York, New York
  • Montefiore Medical Center โ€” The Bronx, New York
  • Levine Cancer Institute, Carolinas HealthCare System โ€” Charlotte, North Carolina
  • Cleveland Clinic โ€” Cleveland, Ohio
  • Oregon Health And Science University โ€” Portland, Oregon
  • University of Pennsylvania โ€” Philadelphia, Pennsylvania

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—