DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers (NCT04165564)
🩺 Plain-English Summary (8th-Grade Level)
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung nodules.
Who can join: Review the eligibility criteria below.
Location: University of Alabama, Birmingham — Birmingham, Alabama
Age range: 46 Years
🧪 Interventions in This Study
- Institutional standard of care (OTHER)
- Biosamples of airway and blood (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (19 Sites)
- University of Alabama, Birmingham — Birmingham, Alabama
- University of California Los Angeles — Los Angeles, California
- VA Greater LA Healthcare System — Los Angeles, California
- Naval Medical Center San Diego — San Diego, California
- University of Iowa — Iowa City, Iowa
- Walter Reed Army Medical Center — Bethesda, Maryland
- VA Boston Healthcare System — Boston, Massachusetts
- University of Michigan — Ann Arbor, Michigan
- Mayo Clinic — Rochester, Minnesota
- Cleveland Clinic — Cleveland, Ohio
- American College of Radiology [Administrative Site] — Philadelphia, Pennsylvania
- University of Pennsylvania School of Medicine — Philadelphia, Pennsylvania
- Temple University — Philadelphia, Pennsylvania
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- Brown University [Administrative Site] — Providence, Rhode Island
- VA Tennessee Valley Healthcare System — Nashville, Tennessee
- MD Anderson Cancer Center [Administrative Site] — Houston, Texas
- Naval Medical Center Portsmouth — Portsmouth, Virginia
- West Virginia University — Morgantown, West Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.