🏛️ Verified NIH Record • Updated 2025-12-04
Cladribine Tablets After Treatment With Natalizumab (CLADRINA) (NCT04178005)
🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: University of Texas Southwestern Medical Center
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to generate hypotheses regarding the safety, efficacy, and immunological impact of cladribine tablets after treatment with natalizumab in patients with relapsing-remitting multiple sclerosis (RRMS) and active secondary progressive multiple sclerosis (active SPMS).
Who can join: Review the eligibility criteria below.
Location: College Park Family Care Center Physicians Group — Overland Park, Kansas
Age range: 18 Years to 60 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- College Park Family Care Center Physicians Group — Overland Park, Kansas
- UT Southwestern Medical center — Dallas, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.