An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus (NCT04192773)
🩺 Plain-English Summary (8th-Grade Level)
This is an exploratory pilot open-label study to identify the signal changes on fMRI of patients with tinnitus and with temporary suppression of the tinnitus with IV lidocaine. Patients will include those with hearing loss (both unilateral and bilateral) and tinnitus, subjects with normal hearing and tinnitus, and control subjects with normal hearing and no tinnitus. Eligible subjects will have functional and subjective data collected at baseline, receive an IV lidocaine infusion, and have functional and subjective data collected post-infusion for comparison and identification of involved neural networks.
Who can join: Review the eligibility criteria below.
Location: Massachusetts Eye and Ear Infirmary — Boston, Massachusetts
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Massachusetts Eye and Ear Infirmary — Boston, Massachusetts
📞 Contact the Study Coordinator
Phone: (617) 573-6016
Email: simonyan_lab@meei.harvard.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Tinnitus
- Management of Acute Tinnitus With Migraine Medications — Orange, California
- Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation — Minneapolis, Minnesota
- Guided ICBT for Adults With Tinnitus in Canada: A Randomized Controlled Trial — London, Ontario
- Noninvasive Therapy for Tinnitus — Miami, Florida
- Somatosensory Tinnitus RCT — Portland, Oregon
- Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia — Aurora, Colorado
Explore by condition: All Tinnitus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.