🏛️ Verified NIH Record • Updated 2025-11-04

Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease (NCT04198922)

Acalabrutinib for Chronic Graft-Versus-Host Disease

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Fred Hutchinson Cancer Center

🩺 Plain-English Summary (8th-Grade Level)

This phase II trial studies how well acalabrutinib works in treating patients with chronic graft versus host disease. Acalabrutinib may be an effective treatment for graft-versus-host disease caused by a stem cell transplant.

Who can join: Review the eligibility criteria below.

Location: Moffitt Cancer Center — Tampa, Florida

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (6 Sites)

  • Moffitt Cancer Center — Tampa, Florida
  • Roswell Park Comprehensive Cancer Center — Buffalo, New York
  • The Ohio State University Wexner Medical Center — Columbus, Ohio
  • Vanderbilt University Medical Center — Nashville, Tennessee
  • The University of Texas MD Anderson Cancer Center — Houston, Texas
  • Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Recurrent Moderate-Severe Chronic Graft Versus Host Disease clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗