🏛️ Verified NIH Record • Updated 2025-05-07
ATG Plus PTCy vs ATG for CGVHD Prophylaxis (NCT04202835)
A Randomized Pilot Trial Comparing Anti-Thymocyte Globulin (ATG) With ATG Plus Post Transplant Cyclophosphamide (PTCy) for Prophylaxis Against Acute and Chronic Graft Versus Host Disease (GVHD)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: McMaster University
🩺 Plain-English Summary (8th-Grade Level)
A Randomized Pilot Trial to test the feasibility of comparing anti-thymocyte globulin plus post transplant cyclophosphamide with anti-thymocyte globulin alone to prevent chronic graft versus host disease.
Who can join: Review the eligibility criteria below.
Location: Kinghorn Cancer Centre, St Vincent's Health Network — Darlinghurst, New South Wales
Age range: 16 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Kinghorn Cancer Centre, St Vincent's Health Network — Darlinghurst, New South Wales
- Royal North Shore Hospital — St Leonards, New South Wales
- Australasian Leukaemia and Lymphoma Group — Melbourne, Victoria
- CancerCare Manitoba — Winnipeg, Manitoba
- Queen Elizabeth II Health Sciences Centre — Halifax, Nova Scotia
- Juravinski Hospital and Cancer Centre — Hamilton, Ontario
- London Health Sciences Centre — London, Ontario
- Hôpital de l'Enfant-Jésus — Québec, Quebec
- Saskatchewan Cancer Agency — Saskatoon, Saskatchewan
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.