Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer (NCT04253483)
A Pilot Study Comparing High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy in Localized Prostate Cancer
🩺 Plain-English Summary (8th-Grade Level)
This phase II trial compares high-dose rate brachytherapy and stereotactic ablative radiotherapy as monotherapy in treating patients with prostate cancer that has not spread to other parts of the body (localized). High-dose rate brachytherapy delivers radiation directly into the prostate within a few minutes by a single radioactive seed through temporarily placed plastic catheters inside the prostate gland. Stereotactic ablative radiotherapy is an external beam radiation method that delivers large doses of radiation to the cancer in a short period of time, usually 5 treatments. This trial aims to find which of these two approaches is better in terms of patient-reported quality of life.
Who can join: Review the eligibility criteria below.
Location: RWJBarnabas Health - Saint Barnabas Medical Center, Livingston — Livingston, New Jersey
Age range: 18 Years
🧪 Interventions in This Study
- High-Dose Rate Brachytherapy (RADIATION)
- Quality-of-Life Assessment (OTHER)
- Questionnaire Administration (OTHER)
- Stereotactic Ablative Radiotherapy (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- RWJBarnabas Health - Saint Barnabas Medical Center, Livingston — Livingston, New Jersey
- Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey
- Rutgers New Jersey Medical School — Newark, New Jersey
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Stage I Prostate Cancer AJCC v8
- Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer — Houston, Texas
- Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners — Houston, Texas
- Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer — Irvine, California
- Vitamin D for Prostate Endocrine Therapy — Newark, Delaware
Explore by condition: All Stage I Prostate Cancer AJCC v8 clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.