Cell-free DNA in Hereditary And High-Risk Malignancies 1 (NCT04261972)
Early Detection of Cancer in High-risk Patients Through Cell-free DNA 1
🩺 Plain-English Summary (8th-Grade Level)
The goal of this study is to develop an effective, sensitive blood test that can detect early tumours in patients with known or suspected hereditary cancer syndromes (HCS). If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection. The study will also use questionnaires and interviews to understand how patients feel about incorporating these tests into routine medical care, and the perceptions of the medical value of test results.
Who can join: Review the eligibility criteria below.
Location: BC Cancer Agency — Vancouver, British Columbia
Age range: 18 Years
🧪 Interventions in This Study
- Next generation sequencing (NGS) (GENETIC)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- BC Cancer Agency — Vancouver, British Columbia
- Eastern Health — St. John's, Newfoundland and Labrador
- IWK Health Centre — Halifax, Nova Scotia
- Sinai Health System — Toronto, Ontario
- University Health Network — Toronto, Ontario
- Women's College Hospital — Toronto, Ontario
- Jewish General Hospital — Montreal, Quebec
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hereditary Cancer Syndrome
- Integrative Sequencing In Germline and Hereditary Tumours — Toronto, Ontario
- Implementation of Population Cancer Genetic Services in Federally Qualified Health Centers (FQHC) — Chicago, Illinois
- Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening — New York, New York
- CfDNA in Hereditary And High-risk Malignancies 2 — Vancouver, British Columbia
Explore by condition: All Hereditary Cancer Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.