๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-20

Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial) (NCT04268550)

A Phase II Study of LOXO-292 in Patients With RET Fusion-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (LUNG-MAP Sub-Study)

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: SWOG Cancer Research Network

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase II LUNG-MAP treatment trial studies how well selpercatinib works in treating patients with RET fusion-positive non-small cell lung cancer that is stage IV or has come back (recurrent). Selpercatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Who can join: Review the eligibility criteria below.

Location: Fairbanks Memorial Hospital โ€” Fairbanks, Alaska

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (306 Sites)

Showing the first 25 of 306 sites.

  • Fairbanks Memorial Hospital โ€” Fairbanks, Alaska
  • University of Arkansas for Medical Sciences โ€” Little Rock, Arkansas
  • Kaiser Permanente-Anaheim โ€” Anaheim, California
  • Sutter Auburn Faith Hospital โ€” Auburn, California
  • Kaiser Permanente-Baldwin Park โ€” Baldwin Park, California
  • Kaiser Permanente-Bellflower โ€” Bellflower, California
  • Alta Bates Summit Medical Center-Herrick Campus โ€” Berkeley, California
  • Kaiser Permanente-Fontana โ€” Fontana, California
  • Palo Alto Medical Foundation-Fremont โ€” Fremont, California
  • Kaiser Permanente - Harbor City โ€” Harbor City, California
  • Kaiser Permanente-Irvine โ€” Irvine, California
  • Loma Linda University Medical Center โ€” Loma Linda, California
  • Kaiser Permanente Los Angeles Medical Center โ€” Los Angeles, California
  • Kaiser Permanente-Cadillac โ€” Los Angeles, California
  • Palo Alto Medical Foundation-Camino Division โ€” Mountain View, California
  • Kaiser Permanente-Ontario โ€” Ontario, California
  • Palo Alto Medical Foundation Health Care โ€” Palo Alto, California
  • Stanford Cancer Institute Palo Alto โ€” Palo Alto, California
  • Kaiser Permanente - Panorama City โ€” Panorama City, California
  • Kaiser Permanente-Riverside โ€” Riverside, California
  • Sutter Roseville Medical Center โ€” Roseville, California
  • Sutter Medical Center Sacramento โ€” Sacramento, California
  • University of California Davis Comprehensive Cancer Center โ€” Sacramento, California
  • Kaiser Permanente-San Diego Zion โ€” San Diego, California
  • California Pacific Medical Center-Pacific Campus โ€” San Francisco, California

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—