The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies (NCT04329728)
An Open Label, Phase 1/2 Study Evaluating Immunomodulatory AVM0703 in Patients With Lymphoid Malignancies (OPAL Study)
🩺 Plain-English Summary (8th-Grade Level)
This is an open-label, Phase 1/2 study designed to characterize the safety, tolerability, Pharmacokinetics(PK), and preliminary antitumor activity of AVM0703 administered as a single intravenous (IV) infusion to patients with lymphoid malignancies.
Who can join: Review the eligibility criteria below.
Location: City of Hope — Duarte, California
Age range: 12 Years to 95 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (11 Sites)
- City of Hope — Duarte, California
- Los Angeles Cancer Network — Los Angeles, California
- UCLA Medical Center of Hematology/Oncology — Los Angeles, California
- Innovative Clinical Research Institute — Whittier, California
- ASCLEPES Research Centers — Weeki Wachee, Florida
- University of Illinois at Chicago Cancer Center — Chicago, Illinois
- Norton Cancer Institute — Louisville, Kentucky
- Oncology Hematology West P.C. dba Nebraska Cancer Specialists — Omaha, Nebraska
- Gabrail Cancer Center Research, — Canton, Ohio
- Baptist Clinical Research Institute — Memphis, Tennessee
- University of Texas(UT) Southwestern-Children's Medical Center — Dallas, Texas
📞 Contact the Study Coordinator
Phone: (206) 851-3942
Email: tdeisher@avmbiotech.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Lymphoid Malignancies clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.