๐๏ธ Verified NIH Record โข Updated 2026-07-06
The Combination of Venetoclax and Obinutuzumab in People With Chronic Lymphocytic Leukemia (CLL) (NCT04447768)
A Phase II: Venetoclax-Based Therapy for the Treatment of Fit Patients With Chronic Lymphocytic Leukemia (CLL) in the Front-Line Setting
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Memorial Sloan Kettering Cancer Center
๐ฉบ Plain-English Summary (8th-Grade Level)
This study will help researchers collect more information about how effective the combination of venetoclax and obinutuzumab is in treating CLL in people who have not received a previous treatment for their cancer.
Who can join: Review the eligibility criteria below.
Location: Stanford University Medical Center (Data collection only) โ Stanford, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (8 Sites)
- Stanford University Medical Center (Data collection only) โ Stanford, California
- Memorial Sloan Kettering Basking Ridge (All protocol activities) โ Basking Ridge, New Jersey
- Memorial Sloan Kettering Monmouth (All protocol activities) โ Middletown, New Jersey
- Memorial Sloan Kettering Commack (All protocol activities) โ Commack, New York
- Memorial Sloan Kettering Westchester (All protocol activities) โ Harrison, New York
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) โ New York, New York
- Memorial Sloan Kettering Nassau (All protocol activities) โ Uniondale, New York
- University of North Carolina โ Chapel Hill, North Carolina
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Chronic Lymphocytic Leukemia (CLL)
- Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax โ Basking Ridge, New Jersey
- A Trial of "Armored" CAR T Cells Targeting CD19 For Patients With Relapsed CD19+ Hematologic Malignancies โ New York, New York
- Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL โ Stamford, Connecticut
- A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL) โ Houston, Texas
- Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib โ Bethesda, Maryland
Explore by condition: All Chronic Lymphocytic Leukemia (CLL) clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.