NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness (NCT04471909)
A Multi-arm, Multi-Center, Non-Randomized, Prospective, Clinical Study to Evaluate the Safety and Effectiveness of the NEXUS Aortic Arch Stent Graft System in Treating Thoracic Aortic Lesions Involving the Aortic Arch
🩺 Plain-English Summary (8th-Grade Level)
Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical graft, in the ascending aorta and with a brachiocephalic trunk native landing zone.
Who can join: Review the eligibility criteria below.
Location: University of Alabama Birmingham — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (32 Sites)
Showing the first 25 of 32 sites.
- University of Alabama Birmingham — Birmingham, Alabama
- University of California San Diego Medical Center — La Jolla, California
- UC Davis Health — Sacramento, California
- Stanford University School of Medicine — Stanford, California
- University of Colorado — Aurora, Colorado
- Hartford Hospital — Hartford, Connecticut
- MedStar Washington Hospital — Washington D.C., District of Columbia
- Advent Health Orlando — Orlando, Florida
- Emory University — Atlanta, Georgia
- The University of Chicago — Chicago, Illinois
- Ascension St. Vincent — Carmel, Indiana
- University of Maryland — Baltimore, Maryland
- Tufts Medical Center — Boston, Massachusetts
- University of Michigan — Ann Arbor, Michigan
- Washington University School of Medicine — St Louis, Missouri
- The Mount Sinai Medical Center — New York, New York
- Northwell Health Lenox Hill Hospital — New York, New York
- University of North Carolina — Chapel Hill, North Carolina
- Atrium Health — Charlotte, North Carolina
- Duke University Medical Center — Durham, North Carolina
- The Lindner Research Center — Cincinnati, Ohio
- University Hospitals of Cleveland — Cleveland, Ohio
- Oregon Health — Portland, Oregon
- University of Pennsylvania — Philadelphia, Pennsylvania
- Lankenau Medical Center — Wynnewood, Pennsylvania
📞 Contact the Study Coordinator
Phone: (612) 280-0208
Email: j.kleine@endospan.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Aortic Dissection
- Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique (STABILISE) — Stanford, California
- GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections — Birmingham, Alabama
- Hemiarch vs Extended Arch in Type 1 Aortic Dissection — London, Ontario
- Feasibility of Endovascular Repair Of Ascending Aortic Pathologies — Long Beach, California
Explore by condition: All Aortic Dissection clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.