🏛️ Verified NIH Record • Updated 2025-07-24

A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma (NCT04522323)

A Phase 1b, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of MEDI5752 in Combination With Axitinib in Subjects With Advanced Renal Cell Carcinoma

🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic Sponsor: MedImmune LLC

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate MEDI5752 in combination with Lenvatinib (or Axitinib), in subjects with advanced renal cell carcinoma.

Who can join: Review the eligibility criteria below.

Location: Research Site — Washington D.C., District of Columbia

Age range: 18 Years to 101 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (20 Sites)

  • Research Site — Washington D.C., District of Columbia
  • Research Site — Fort Myers, Florida
  • Research Site — St Louis, Missouri
  • Research Site — New York, New York
  • Research Site — Cleveland, Ohio
  • Research Site — Hershey, Pennsylvania
  • Research Site — Nashville, Tennessee
  • Research Site — Frankston,
  • Research Site — Waratah,
  • Research Site — Villejuif,
  • Research Site — Barcelona,
  • Research Site — Barcelona,
  • Research Site — Barcelona,
  • Research Site — Barcelona,
  • Research Site — Córdoba,
  • Research Site — Madrid,
  • Research Site — Madrid,
  • Research Site — Sabadell,
  • Research Site — Seville,
  • Research Site — Valencia,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗