A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis (NCT04527380)
Multicenter, Open-label, Efficacy, Safety, Tolerability, and Pharmacokinetic Study of Subcutaneous Ixekizumab With Adalimumab Reference Arm, in Children With Juvenile Idiopathic Arthritis Subtypes of Enthesitis-related Arthritis (Including Juvenile-Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis
🩺 Plain-English Summary (8th-Grade Level)
The reason for this study is to see if the study drug ixekizumab is safe and effective in children with juvenile idiopathic arthritis (JIA) categories of enthesitis-related arthritis (ERA) (including juvenile onset ankylosing spondylitis \[JoAS\]) and juvenile psoriatic arthritis (JPsA).
Who can join: Review the eligibility criteria below.
Location: Instituto CAICI SRL Loc. 15 — Rosario, Santa Fe Province
Age range: 2 Years to 17 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (43 Sites)
Showing the first 25 of 43 sites.
- Instituto CAICI SRL Loc. 15 — Rosario, Santa Fe Province
- Centro Medico Privado de Reumatologia Loc. 20 — San Miguel de Tucumán, Tucumán Province
- Cliniques universitaires Saint-Luc — Brussels, Bruxelles-Capitale, Région de
- UZ Gent — Ghent, Oost-Vlaanderen
- UZ Leuven — Leuven, Vlaams-Brabant
- Oddeleni revmatologie deti a dospelych Loc. 1 — Prague, Praha 5
- Dětská klinika Loc. 11 — Olomouc,
- Klinika detskeho a dorostoveho lekarstvi Loc. 1 — Prague,
- Aarhus Universitetshospital, Skejby — Aarhus, Central Jutland
- Service rhumatologie Loc. — Bron, Auvergne-Rhône-Alpes
- Service de consultation pédiatrique Loc. 1 — Montpellier, Hérault
- Rhumatologie pediatrique et CEREMAIA Loc. 1 — Le Kremlin-Bicêtre, Paris
- RHUMATOLOGIE Loc. 1 — Poitiers, Vienne
- Centre d'Investigation Clinique Loc. 1 — Paris,
- Universitaetsklinikum Freiburg — Freiburg im Breisgau, Baden-Wurttemberg
- Asklepios Klinik Sankt Augustin — Sankt Augustin, North Rhine-Westphalia
- St. Josef-Stift Sendenhorst — Sendenhorst, North Rhine-Westphalia
- Helios Klinikum Berlin-Buch — Berlin,
- Charité Campus Virchow-Klinikum — Berlin,
- Klinikum Bremen-Mitte — Bremen,
- Praxis Kinder- und Jugendrheumatologie Dr. Ivan Foeldvari — Hamburg,
- University of Naples Federico II — Naples, Campania
- IRCCS Istituto Giannina Gaslini — Genoa, Liguria
- Centro Specialistico Ortopedico Traumatologico Gaetano Pini - CTO — Milan, Lombardy
- Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico — Milan, Lombardy
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Juvenile Psoriatic Arthritis
- A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis — Lancaster, California
- Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA). — Loma Linda, California
- A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab — Little Rock, Arkansas
Explore by condition: All Juvenile Psoriatic Arthritis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.