🏛️ Verified NIH Record • Updated 2025-03-27
Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients (NCT04534959)
Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients (SAVE-O2)
🔵 Active, Not Recruiting Phase3 📋 Clinical Research Protocol Sponsor: University of Colorado, Denver
🩺 Plain-English Summary (8th-Grade Level)
The objective is to determine the effectiveness of a multimodal educational intervention to reduce supplemental oxygen use in critically injured patients. Investigators will also evaluate the safety and clinical effectiveness of the more targeted use of oxygen therapy.
Who can join: Review the eligibility criteria below.
Location: University of Alabama-Birmingham Medical Center — Birmingham, Alabama
Age range: 18 Years to 120 Years
🧪 Interventions in This Study
- Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg) (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- University of Alabama-Birmingham Medical Center — Birmingham, Alabama
- Denver Health — Denver, Colorado
- University of Cincinnati Medical Center — Cincinnati, Ohio
- Oregon Health and Sciences University — Portland, Oregon
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- Vanderbilt University Medical Center — Nashville, Tennessee
- Brooke Army Medical Center — Fort Sam Houston, Texas
- The University of Texas Health Science Center at Houston — Houston, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Critical Illness
- 12-hour Time Limited Feeding in Critical Care — Kansas City, Kansas
- Strategy to Avoid Excessive Oxygen in Major Burn Patients — Birmingham, Alabama
- Family Integration in Therapy Activities in the Intensive Care Unit: The FIT-ICU Feasibility Study — Brantford, Ontario
- Real-time NOMA Evaluation — Pittsburgh, Pennsylvania
- Amino Acid Nutrition in the Critically-ill — Montreal, Quebec
- Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors — Seattle, Washington
Explore by condition: All Critical Illness clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.