ποΈ Verified NIH Record β’ Updated 2026-07-30
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (NCT04557098)
TECLIMMY1001-P3: A Phase 1/2, First-in-Human, Open-Label, Dose Escalation Study of Teclistamab, a Humanized BCMA x CD3 Bispecific Antibody, in Subjects With Relapsed or Refractory Multiple Myeloma
π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC
π©Ί Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy of teclistamab at the recommended Phase 2 dose (RP2D).
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham β Birmingham, Alabama
Age range: 18 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (51 Sites)
Showing the first 25 of 51 sites.
- University of Alabama at Birmingham β Birmingham, Alabama
- City of Hope β Duarte, California
- University of California San Francisco β San Francisco, California
- Stanford University Medical Center β Stanford, California
- Winship Cancer Institute Emory University β Atlanta, Georgia
- Barbara Ann Karmanos Cancer Institute β Detroit, Michigan
- Icahn School of Medicine at Mount Sinai Program for the Protection of Human Subjects β New York, New York
- Memorial Sloan-Kettering Cancer Center β New York, New York
- Levine Cancer Institute β Charlotte, North Carolina
- University of Pennsylvania β Philadelphia, Pennsylvania
- Universitair Ziekenhuis Gent - UZ GENT β Ghent,
- Universitaire Ziekenhuizen Leuven β Leuven,
- Arthur J E Child Comprehensive Cancer Centre β Calgary, Alberta
- Cross Cancer Institute β Edmonton, Alberta
- University Health Network UHN Princess Margaret Cancer Centre β Toronto, Ontario
- McGill University Health Centre β Montreal, Quebec
- Peking University First Hospital β Beijing,
- West China Hospital Si Chuan University β Chengdu,
- Sun Yat -Sen University Cancer Center β Guangzhou,
- First affiliated Hospital of Zhejiang University β Hangzhou,
- Shanghai Changzheng Hospital β Shanghai,
- Shengjing Hospital Of China Medical University β Shenyang,
- Tianjin Medical University Cancer Institute and Hospital β Tianjin,
- The Second Affiliated Hospital of Xi'an Jiaotong University β Xi'an,
- Centre Hospitalier RΓ©gional Universitaire de Lille, HΓ΄pital Claude Huriez β Lille,
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hematological Malignancies
- Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma β Birmingham, Alabama
- Feasibility of the Use of Weighted Blankets to Improve Sleep Among Patients With Hematological Malignancies β Houston, Texas
- Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma β Duarte, California
- Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies β Houston, Texas
- A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma β Birmingham, Alabama
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π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.