ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis) (NCT04561518)
ConTTRibute: A Global Observational Multicenter Long-Term Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to: * Describe epidemiological and clinical characteristics, natural history and real-world clinical management of ATTR amyloidosis patients * Characterize the safety and effectiveness of patisiran and vutrisiran as part of routine clinical practice in the real-world clinical setting * Describe disease emergence/progression in pre-symptomatic carriers of a known disease-causing transthyretin (TTR) variant
Who can join: Review the eligibility criteria below.
Location: Clinical Trial Site — La Jolla, California
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (40 Sites)
Showing the first 25 of 40 sites.
- Clinical Trial Site — La Jolla, California
- Clinical Trial Site — Los Angeles, California
- Clinical Trial Site — Jacksonville, Florida
- Clinical Trial Site — Iowa City, Iowa
- Clinical Trial Site — Kansas City, Kansas
- Clinical Trial Site — Baltimore, Maryland
- Clinical Trial Site — Boston, Massachusetts
- Clinical Trial Site — New York, New York
- Clinical Trial Site — Durham, North Carolina
- Clinical Trial Site — Columbus, Ohio
- Clinical Trial Site — Philadelphia, Pennsylvania
- Clinical Trial Site — Austin, Texas
- Clinical Trial Site — Houston, Texas
- Clinical Trial Site — Salvador,
- Clinical Trial Site — São Paulo,
- Clinical Trial Site — Sofia,
- Clinical Trial Site — Aarhus,
- Clinical Trial Site — Copenhagen,
- Clinical Trial Site — Bordeaux,
- Clinical Trial Site — Bron,
- Clinical Trial Site — Créteil,
- Clinical Trial Site — Le Kremlin-Bicêtre,
- Clinical Trial Site — Marseille,
- Clinical Trial Site — Berlin,
- Clinical Trial Site — Giessen,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Transthyretin-Mediated Amyloidosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.